Liver perfusion machines
They keep the liver in near-physiological conditions after retrieval, to preserve it better.
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Research & innovation
Better care through research
Intense clinical and experimental research, working directly in the service of care.
▶ Research at the Centre in video
Research is part of care. Here, the questions raised at the bedside shape our projects, and the results come back to the operating room.
This work is supported by two Inserm–Université Paris-Saclay joint research units and a clinical research unit, which coordinates the trials and studies run at the Centre.
2 Inserm units · Paris-SaclayClinical research unitClinical trials
Clinical and experimental researchInnovation
Repairing the liver before transplant
The Centre uses machines that recreate physiological perfusion conditions to assess and improve grafts.
Graft rehabilitation
A dedicated platform to assess, and sometimes recover, livers intended for transplantation.
From static preservation to dynamic perfusion
For more than 30 years, preserving a liver graft — the future transplanted organ — has relied on a specific fluid in which the graft is kept statically, in a cold environment (4 to 10 °C).
Over the past decade, new dynamic techniques have emerged: machines that perfuse the graft continuously using a pump and an oxygenator. Oxygenated hypothermic perfusion extends preservation time and improves the graft's recovery of function after transplantation. Other techniques, under normothermic conditions (37 °C), open the way to repairing sub-optimal grafts before transplantation.
Augmented operating room
The operating room of tomorrow, with the BOPA chair
The Centre takes part in the "Augmented Operating Room" (BOPA) innovation chair, which designs and tests digital innovations in the operating room: artificial intelligence, digital twins, vision and robotics, in the service of the quality and safety of care.
Discover the BOPA chairPhoto à venirThe augmented operating room (BOPA)